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| QAD | Document (PF QuickArt) |
| QAG | Quick Access Group data file (Norton Desktop) |
| QAP | Application file (Omnis Quartz) |
| QBB | QuickBooks backup file |
| QBE | Saved Query (Quattro Pro) |
| QBE | Saved query (dBase IV) |
| QBM | QuickBooks Portable Company file |
| QBO | Compiled query (dBase IV) |
| QBS | Program file (Microsoft QuickBasic) |
| QBW | Spreadsheet data (QuickBooks for Windows) |
| QCP | Voice file (Qualcomm Pure Voice) |
| QD0 | Data file-segment 10 (Omnis Quartz) |
| QD1 | Data file segment 1 (Omnis Quartz) |
| QD2 | Data file segment 2 (Omnis Quartz) |
| QD3 | Data file segment 3 (Omnis Quartz) |
| QD3D | QuickDraw 3D Metafile (Apple) |
| QD4 | Data file segment 4 (Omnis Quartz) |
| QD5 | Data file segment 5 (Omnis Quartz) |
| QD6 | Data file segment 6 (Omnis Quartz) |
| QD7 | Data file segmnet 7 (Omnis Quartz) |
| QD8 | Data file segment 8 (Omnis Quartz) |
| QD9 | Data file segment 9 (Omnis Quartz) |
| QDF | Data file (Quicken) |
| QDK | Backup of startup files (QEMM) |
| QDT | Data file from the Quicken UK Accountancy/Tax/Invoice program (QuickBooks) |
| QDV | Graphics file (Steve Blackstock Giffer) |
| QEF | Query file (Microsoft Excel) |
| QEL | Electronic library file (Quicken) |
| QFL | Document (FAMILY LAWYER) |
| QFX | Fax (QuickLink) |
| QIC | Backup file (Microsoft) |
| QIF | Import file (Quicken) |
| QIF | Image (MIME)(QuickTime) |
| QLB | Library file (Microsoft C/C++) |
| QLB | Library file (Quick) |
| QLC | Data (PostScript help file) |
| QLP | Printer driver (QuickLink) |
| QM | Motion file (Quality) |
| QM4 | Option or services file (QMail 4.x Mail Door) |
| QPH | Quicken Price History file |
| QPR | Print queue device driver (OS/2) |
| QPR | Generated query program (Microsoft FoxPro) |
| QPX | Compiled query program (Microsoft FoxPro) |
| QQT | Qardware definition file (Quick Qard Technology) |
| QRP | Report file (Liberty for Windows 2.0) |
| QRP | Report builder file (Centura) |
| QRS | Equation Editor support file (WordPerfect for Windows) |
| QRT | QRT graphics file (Ray Tracer) |
| QRY | Query (dBase IV) |
| QRY | Query (Microsoft) |
| QRY | Crystal Sql Designer file (script) |
| QSD | Datafile (Quicken) |
| QST | Tab file (Quake Spy) |
| QT | Movie file (QuickTime) |
| QTI | Image file (QuickTime) |
| QTIF | Image file (QuickTime) |
| QTM | Movie file (QuickTime) |
| QTP | Preferences file (QuickTime) |
| QTS | Image file (QuickTime) |
| QTS | PICT image file (Macintosh) |
| QTX | Image file (QuickTime) |
| QUE | Perseus Development Corporation SurveySolutions Questionnaire |
| QUE | CuteFTP Queue File |
| QWK | Message file (QWK Reader) |
| QXD | Data file (QuarkXpress) |
| QXL | Element library (QuarkXpress) |
| QXP | Project file (replaces QXD file as of QuarkXPress 6) |
| QXT | Template file (QuarkXpress) |
