File Extension SPSS File Format SPSS file SPSS stands for SPSS file. This was last updated in March 2012 By Margaret Rouse Browse File Extensions Alphabetically: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # Ask a Question. Find an Answer. Ask your peers a question about this file extension. Ask a Question SPSS Data in Data Editor BUT Unable to Analyze Are your analytical assets and processes visible, automated and secure? How do you currently collect behavioral, attitudinal, transactional and demographic data?